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Helix Biopharma Corp.
Bay Adelaide Centre - North Tower 40
Temperance Street, Suite 2700 Toronto
Phone: (604) 684-2181p:604 684-2181 TORONTO, ON  M5H 0B4  Canada Ticker: HBPHBP
Business Summary
Helix BioPharma Corp. is a clinical-stage biopharmaceutical company. The Company is focused on developing therapies in the field of immune oncology for the prevention and treatment of cancer based on its proprietary technological platform DOS47. DOS47 is a broad anti-cancer antibody drug conjugate (ADC) platform. DOS47 is based upon a naturally occurring enzyme isolated from the jack bean plant called urease that breaks down a natural substance found in the body, urea, into metabolites that include ammonium and hydroxyl ions. By doing so at the site of cancerous tissues in the body, DOS47 is designed to stimulate an increase in the pH of the microenvironment surrounding the cancerous cells, effectively reversing the acidic extracellular conditions that are believed to act to defend the tumor. Its pipeline includes L-DOS47 monotherapy NSCLC, L-DOS47 combo PEM/CARBO NSCLC, L-DOS47 DOXO combo Pancreas, and L-DOS47 combo Immune Checkpoints.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-----

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
7/31/20247/31/2024YesYes---

Industries
SIC Code Description
8731 Commercial physical and biological research
2834 Pharmaceutical preparations

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Chief Executive Officer, Director JacekAntas 12/8/2022 4/18/2022
Independent Director Margaret I.Laube 12/8/2022 12/8/2022
Independent Director JerzyLeszczynski 4/18/2022 4/18/2022
Independent Director ChristopherMaciejewski 4/18/2022 4/18/2022

Business Names
Business Name
HBP
Helix Biopharma Corp.
Helix Polska
Helix Polska sp.z o.o
Helix Product Development(Ireland) Limited

General Information
Number of Employees: 7 (As of 7/31/2024)
Outstanding Shares: 49,021,550 (As of 8/16/2024)
Shareholders: 141
Stock Exchange: TSE
Fax Number: (905) 841-2244


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Wednesday, November 20, 2024